| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 8/27/2021 |
vs
Waterloo East #223
|
W 35-13 | Memorial Stadium | |
| 9/3/2021 |
vs
Cedar Falls #96
|
L 14-52 | UNI-Dome | |
| 9/10/2021 |
vs
Davenport West #292
|
W 45-7 | Memorial Stadium | Homecoming |
| 9/17/2021 |
vs
Dubuque Senior #126
|
L 14-41 | Dubuque Senior High School | |
| 9/24/2021 |
vs
Southeast Polk #15
|
L 7-49 | Southeast Polk High School | |
| 10/1/2021 |
vs
Prairie #62
|
L 7-55 | Memorial Stadium | |
| 10/7/2021 |
@
Cedar Rapids Jefferson #311
|
W 69-14 | Kingston Stadium | |
| 10/15/2021 |
vs
Dubuque Hempstead #175
|
L 14-28 | Memorial Stadium | Senior Night |
| 10/22/2021 |
@
Ottumwa #270
|
W 70-0 | Schafer Stadium |
