| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 8/27/2021 |
vs
Pleasant Valley #65
|
W 27-21 | Cedar Rapids Prairie High School | |
| 9/3/2021 |
vs
Dubuque Senior #126
|
W 28-14 | Dubuque Senior High School | |
| 9/10/2021 |
vs
Cedar Falls #96
|
L 21-24 | Cedar Rapids Prairie High School | |
| 9/17/2021 |
vs
Bettendorf #103
|
W 54-20 | Cedar Rapids Prairie High School | |
| 9/24/2021 |
@
Ottumwa #270
|
W 1-0 | Schafer Stadium | FORFEIT |
| 10/1/2021 |
@
Waterloo West #206
|
W 55-7 | Memorial Stadium | |
| 10/8/2021 |
vs
Southeast Polk #15
|
L 20-21 | Cedar Rapids Prairie High School | |
| 10/15/2021 |
vs
Iowa City West #230
|
W 50-14 | Cedar Rapids Prairie High School | |
| 10/22/2021 |
@
Linn-Mar #68
|
W 36-20 | Linn-Mar Stadium | Senior Night |
| 10/29/2021 |
vs
Bettendorf #103
|
W 24-6 | Cedar Rapids Prairie High School | 5A - First Round |
| 11/5/2021 |
vs
Ankeny #29
|
L 7-37 | Cedar Rapids Prairie High School | 5A- Quarterfinals |
