| Date | Opponent(s) | Result | Caption | Location | Transportation | |
|---|---|---|---|---|---|---|
| 8/27/21 |
@
Xavier
|
L 14-28 | Xavier High School | |||
| 9/3/21 |
vs
North Scott
|
L 13-33 |
Non district game |
Western Dubuque High School | ||
| 9/10/21 |
vs
Iowa City Liberty
|
W 21-10 | Liberty High School | |||
| 9/17/21 |
vs
Dubuque Hempstead
|
W 65-35 | Western Dubuque High School | |||
| 9/24/21 |
@
Marion
|
W 41-0 | Marion Track & Field Complex | |||
| 10/1/21 |
vs
Decorah
|
L 14-19 | Western Dubuque High School | |||
| 10/8/21 |
@
Waterloo East
|
W 55-21 |
Staff Appreciation |
Memorial Stadium | ||
| 10/15/21 |
vs
Waverly-Shell Rock
|
L 39-55 | Western Dubuque High School | |||
| 10/22/21 |
@
Mason City
|
L 22-38 |
Senior Night |
Mason City High School |
