| Date | Opponent(s) | Result | Caption | Location | Transportation | |
|---|---|---|---|---|---|---|
| 8/27/21 |
vs
Winterset
|
L 3-26 | Carlisle High School | |||
| 9/3/21 |
vs
Lewis Central
|
L 22-70 | Lewis Central High School | |||
| 9/10/21 |
@
Knoxville
|
W 62-6 | Knoxville High School | |||
| 9/17/21 |
vs
Des Moines Lincoln
|
W 35-6 |
Homecoming |
Carlisle High School | ||
| 9/24/21 |
@
Bondurant-Farrar
|
L 29-39 |
Youth Cheer |
Bondurant-Farrar High School | ||
| 10/1/21 |
vs
Boone
|
W 41-18 | Carlisle High School | |||
| 10/8/21 |
vs
Indianola
|
L 14-38 | Carlisle High School | |||
| 10/15/21 |
@
Norwalk
|
W 21-14 | Norwalk High School | |||
| 10/22/21 |
vs
Perry
|
W 70-6 |
Senior Night |
Carlisle High School | ||
| 10/29/21 |
vs
Indianola
|
L 0-41 |
4A - First Round |
Indianola Stadium |
