| Date | Opponent(s) | Result | Caption | Location | Transportation | |
|---|---|---|---|---|---|---|
| 8/27/21 |
vs
Newton
|
L 0-41 | Ken Locke Stadium | |||
| 9/3/21 |
@
Oskaloosa
|
L 0-35 | Oskaloosa - Lacey Sports Complex | |||
| 9/10/21 |
vs
Carlisle
|
L 6-62 | Knoxville High School | |||
| 9/17/21 |
vs
Fairfield
|
L 22-42 | Fairfield High School | |||
| 9/24/21 |
vs
Creston
|
L 0-49 | Knoxville High School | |||
| 10/1/21 |
@
Saydel
|
W 24-14 | Saydel High School | |||
| 10/8/21 |
@
Atlantic
|
L 6-42 |
Homecoming |
Atlantic Middle School | ||
| 10/15/21 |
vs
ADM
|
L 0-52 | Knoxville High School | |||
| 10/22/21 |
vs
Harlan Community
|
L 0-76 | Knoxville High School |
