| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 12/3/2021 |
vs
Alta-Aurelia #282
|
W 56-21 | St. Mary's High School | |
| 12/7/2021 |
@
GTRA #231
|
W 46-30 | Graettinger/Terril High School | |
| 12/14/2021 |
@
Sioux Central #77
|
W 48-30 | Sioux Central High School | |
| 12/16/2021 |
vs
River Valley #259
|
W 54-11 | St. Mary's High School | |
| 12/17/2021 |
@
Southeast Valley #295
|
W 43-33 | Southeast Valley High School | |
| 12/20/2021 |
vs
West Bend-Mallard #240
|
W 36-22 | St. Mary's High School | |
| 1/3/2022 |
@
Ar-We-Va #314
|
W 64-14 | Ar-We-Va High School | |
| 1/6/2022 |
@
Whiting #345
|
W 61-20 | Whiting Senior High School | |
| 1/7/2022 |
vs
South Central Calhoun #74
|
W 42-37 | St. Mary's High School | |
| 1/11/2022 |
@
Alta-Aurelia #282
|
W 51-29 | Alta-Aurelia High School | |
| 1/18/2022 |
@
Newell-Fonda #3
|
L 48-52 | Newell-Fonda Community School | |
| 1/21/2022 |
vs
Manson-NW Webster #209
|
W 40-26 | St. Mary's High School | |
| 1/24/2022 |
@
East Sac County #235
|
W 72-37 | East Sac County High School | |
| 1/25/2022 |
vs
GTRA #231
|
W 45-12 | St. Mary's High School | |
| 1/27/2022 |
@
Pocahontas Area #117
|
W 53-46 | Pocahontas Area High School | |
| 1/29/2022 |
@
Siouxland Christian #321
|
W 61-23 | Siouxland Christian School | |
| 2/1/2022 |
vs
Sioux Central #77
|
W 45-23 | St. Mary's High School | |
| 2/4/2022 |
@
Emmetsburg #139
|
W 41-25 | Emmetsburg High School | |
| 2/7/2022 |
vs
Ridge View #57
|
W 53-48 | St. Mary's High School | |
| 2/8/2022 |
@
West Bend-Mallard #240
|
W 70-45 | West Bend-Mallard High School | |
| 2/10/2022 |
vs
Harris-Lake Park #300
|
W 52-21 | St. Mary's High School | Class 1A - Region 1 First Round |
| 2/15/2022 |
vs
Gehlen Catholic #143
|
W 53-47 | St. Mary's High School | Class 1A - Region 1 Quarterfinal |
| 2/18/2022 |
vs
Westwood #54
|
W 62-39 | OABCIG Senior High School | Class 1A - Region 1 Semifinal |
| 2/23/2022 |
vs
MMCRU #5
|
L 31-49 | Cherokee High School | Class 1A - Region 1 Championship |
