| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 11/18/2021 |
@
Washington #284
|
4:00 PM CT | Washington High School | Scrimmage |
| 11/30/2021 |
@
Tipton #312
|
W 58-28 | Tipton Middle School | |
| 12/3/2021 |
@
Wilton #147
|
W 57-54 | Wilton High School | |
| 12/6/2021 |
@
Mount Vernon #102
|
L 50-53 | Mount Vernon High School | |
| 12/7/2021 |
@
Mid-Prairie #134
|
W 55-46 | Mid-Prairie High School | |
| 12/10/2021 |
@
Camanche #271
|
W 53-12 | Camanche High School | |
| 12/14/2021 |
vs
Durant #217
|
W 61-19 | Iowa City Regina High School | |
| 12/16/2021 |
@
Solon #62
|
L 51-57 | Solon High School | |
| 12/17/2021 |
vs
Northeast #255
|
W 65-38 | Iowa City Regina High School | |
| 12/21/2021 |
@
Bellevue #151
|
W 53-37 | Bellevue Middle + High School | |
| 1/4/2022 |
@
Cascade #92
|
W 31-28 | Cascade High School | |
| 1/7/2022 |
@
West Liberty #100
|
W 37-25 | West Liberty High School | |
| 1/8/2022 |
vs
Monticello #142
|
L 46-50 | Iowa City Regina High School | |
| 1/11/2022 |
@
West Branch #125
|
W 55-43 | West Branch High School | |
| 1/18/2022 |
vs
Wilton #147
|
W 74-53 | Iowa City Regina High School | |
| 1/20/2022 |
vs
Tipton #312
|
W 39-38 | Iowa City Regina High School | |
| 1/21/2022 |
vs
Anamosa #352
|
W 68-25 | Iowa City Regina High School | |
| 1/25/2022 |
vs
Mid-Prairie #134
|
W 52-31 | Iowa City Regina High School | |
| 1/28/2022 |
@
Durant #217
|
W 43-21 | Durant High School | |
| 1/29/2022 |
vs
North Cedar #333
|
W 66-20 | Iowa City Regina High School | Senior Night |
| 2/4/2022 |
vs
West Liberty #100
|
L 38-44 | Iowa City Regina High School | |
| 2/8/2022 |
vs
West Branch #125
|
W 41-31 | Iowa City Regina High School | |
| 2/15/2022 |
vs
Van Buren County #254
|
W 64-16 | Iowa City Regina High School | Class 2A - Region 6 |
| 2/18/2022 |
vs
West Branch #125
|
W 48-40 | Iowa City Regina High School | Class 2A - Region 6 |
| 2/23/2022 |
vs
Mediapolis #126
|
W 63-51 | Muscatine High School | Class 2A - Region 6 Championship |
| 3/1/2022 |
vs
Panorama #30
|
L 38-46 | Wells Fargo Arena | 2A - State Quarterfinal |
