| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 11/22/2021 |
@
Meskwaki Settlement #199
|
L 9-46 | Meskwaki Settlement School | |
| 11/29/2021 |
@
Alburnett #187
|
L 9-52 | Alburnett High School | |
| 12/3/2021 |
vs
Clarksville #210
|
L 19-61 | Don Bosco High School | |
| 12/6/2021 |
@
Valley Lutheran #354
|
W 32-22 | Valley Lutheran School | |
| 12/7/2021 |
@
Waterloo Christian #236
|
L 9-51 | Waterloo Christian School | |
| 12/21/2021 |
@
Dunkerton #289
|
L 17-55 | Dunkerton High School | Coaches vs. Cancer |
| 12/22/2021 |
@
Riceville #172
|
L 8-44 | Riceville High School | |
| 1/3/2022 |
vs
Colo-Nesco #304
|
L 9-39 | Don Bosco High School | Rescheduled |
| 1/4/2022 |
@
Tripoli #297
|
L 28-37 | Tripoli High School | |
| 1/10/2022 |
vs
Belle Plaine #239
|
L 0-1 | Don Bosco High School | FORFEIT |
| 1/15/2022 |
vs
Independence #223
|
L 10-60 | Don Bosco High School | Varsity Only |
| 1/17/2022 |
@
Clarksville #210
|
L 14-57 | Clarksville High School | |
| 1/18/2022 |
vs
Waterloo Christian #236
|
L 18-53 | Don Bosco High School | |
| 1/20/2022 |
vs
Janesville #318
|
W 25-23 | Don Bosco High School | Rescheduled Date/Time |
| 1/21/2022 |
vs
Tripoli #297
|
L 40-46 | Don Bosco High School | |
| 1/24/2022 |
vs
Valley Lutheran #354
|
W 49-4 | Don Bosco High School | |
| 1/25/2022 |
vs
Riceville #172
|
L 12-63 | Don Bosco High School | |
| 1/28/2022 |
@
Janesville #318
|
L 28-51 | Janesville High School | Senior Night |
| 2/1/2022 |
vs
Dunkerton #289
|
L 28-42 | Don Bosco High School | |
| 2/3/2022 |
@
North Tama #270
|
L 19-47 | North Tama High School | Senior Night |
| 2/10/2022 |
vs
Belle Plaine #239
|
L 17-42 | Belle Plaine High School | Class 1A - Region 5 First Round |
