| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 8/19/2022 |
vs
Woonsocket/Wessington Springs/Sanborn Central #52
|
W 37-8 | Mount Vernon | |
| 8/26/2022 |
@
Miller/Highmore-Harrold #100
|
W 30-13 | Bob Schroeder Field | Parent's Night |
| 9/2/2022 |
vs
Tripp-Delmont/Armour/Andes Central/Dakota Christian #123
|
W 50-0 | Mount Vernon | @ Mt Vernon |
| 9/9/2022 |
vs
Jim River #83
|
W 30-7 | Mount Vernon | Homecoming |
| 9/17/2022 |
@
Rapid City Christian #75
|
W 52-21 | Rapid City Christian School | |
| 9/23/2022 |
@
Tri-Valley #64
|
W 32-6 | Tri-Valley High School | |
| 9/30/2022 |
@
Wagner #113
|
W 48-24 | Wagner High School | Senior Night |
| 10/14/2022 |
vs
Winner #3
|
L 8-34 | Mount Vernon | Senior Night |
| 10/20/2022 |
vs
Tri-Valley #64
|
W 38-10 | Mount Vernon | Class 11B - State First Round |
| 10/27/2022 |
vs
McCook Central/Montrose #11
|
L 6-38 | Mount Vernon | Class 11B - State Quarterfinal |
