| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 8/27/2021 |
vs
Vermillion #53
|
L 0-38 | Sisseton High School | |
| 9/3/2021 |
vs
Dell Rapids #45
|
L 0-40 | Sisseton High School | |
| 9/10/2021 |
@
Dakota Hills #135
|
L 20-29 | Waubay School Gym | Homecoming |
| 9/17/2021 |
@
Dakota Valley #119
|
L 12-45 | Dakota Valley High School | Homecoming Game |
| 9/24/2021 |
vs
Tri-Valley #63
|
L 0-42 | Sisseton High School | Homecoming |
| 10/2/2021 |
@
Chamberlain #126
|
L 0-48 | Chamberlain High School | |
| 10/8/2021 |
@
Deuel #93
|
L 0-42 | Cardinal Field | Parent's Night |
| 10/15/2021 |
vs
Groton Area #71
|
L 6-60 | Sisseton High School | Senior/Parents Night |
| 10/21/2021 |
vs
Milbank #48
|
L 0-42 | Sisseton High School |
