| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 8/27/2021 |
@
Fort Dodge #82
|
L 13-28 | Fort Dodge Senior High School | |
| 9/3/2021 |
@
Spencer #54
|
L 8-41 | Spencer Senior High School | |
| 9/10/2021 |
vs
Charles City #121
|
W 35-0 | Mason City High School | |
| 9/17/2021 |
vs
Webster City #36
|
L 3-36 | Mason City High School | |
| 9/24/2021 |
@
Decorah #52
|
L 14-33 | Decorah High School | Homecoming |
| 10/1/2021 |
vs
Waterloo East #223
|
W 35-6 | Mason City High School | |
| 10/8/2021 |
@
Waverly-Shell Rock #20
|
L 20-64 | Waverly-Shell Rock Senior High School | |
| 10/15/2021 |
@
Marion #222
|
W 22-21 | Marion Track & Field Complex | |
| 10/22/2021 |
vs
Western Dubuque #123
|
W 38-22 | Mason City High School | Senior Night |
