| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 4/4/2022 |
@
Mount Pleasant #165
|
W 6-0 | Columbus High School | |
| 4/7/2022 |
@
Mid-Prairie #82
|
L 0-1 | Wellman Rotary Soccer Fields | |
| 4/11/2022 |
vs
Tipton #140
|
W 1-0 | Columbus High School | |
| 4/14/2022 |
@
Mediapolis #109
|
L 1-3 | Mediapolis High School | |
| 4/18/2022 |
vs
Highland #171
|
W 6-1 | Columbus High School | |
| 4/19/2022 |
@
Sigourney #170
|
W 5-1 | Sigourney High School | |
| 4/21/2022 |
vs
Wapello #156
|
W 10-3 | Columbus High School | |
| 4/25/2022 |
@
Hillcrest Academy #145
|
W 2-1 | Hillcrest Academy | |
| 4/29/2022 |
@
Burlington Notre Dame #40
|
L 0-8 | Burlington Notre Dame High School | |
| 5/2/2022 |
@
Wapello #156
|
W 7-2 | Wapello Athletic Complex | |
| 5/5/2022 |
vs
Central Lee #151
|
L 1-2 | Columbus High School | |
| 5/9/2022 |
@
Danville #164
|
W 8-4 | Danville Jr/Sr High School | |
| 5/12/2022 |
@
Washington #100
|
W 1-0 | Washington Wellness Park | |
| 5/13/2022 |
vs
Wapello #156
|
W 5-0 | Columbus High School | SEISC Tournament |
| 5/14/2022 |
@
Mediapolis #109
|
L 1-5 | Burlington Notre Dame High School | Conference Tournament |
| 5/19/2022 |
vs
Centerville #152
|
W 7-2 | Burlington Notre Dame High School | 1A-5 First Round |
| 5/23/2022 |
vs
Mediapolis #109
|
W 1-0 | Mediapolis High School | 1A-5 Second Round |
| 5/25/2022 |
vs
Burlington Notre Dame #40
|
L 0-5 | Burlington Notre Dame High School | 1A-5 Championship |
