| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 8/19/2022 |
vs
Center Point-Urbana #195
|
5:00 PM CT | Central DeWitt High School | Scrimmage |
| 8/26/2022 |
vs
Davenport Central #309
|
W 46-0 | Central DeWitt High School | |
| 9/2/2022 |
@
Camanche #228
|
W 42-24 | Camanche High School | |
| 9/9/2022 |
@
Clinton #283
|
W 37-14 | Coan Field | |
| 9/16/2022 |
vs
Marion #120
|
L 13-20 | Central DeWitt High School | Homecoming |
| 9/23/2022 |
vs
Assumption #116
|
L 10-31 | Central DeWitt High School | Teacher Appreciation & Youth Recognition Night |
| 9/30/2022 |
@
Maquoketa #261
|
W 42-21 | Goodenow Field | |
| 10/7/2022 |
vs
Vinton-Shellsburg #233
|
W 24-0 | Central DeWitt High School | Pink Out Cancer Awareness Night |
| 10/14/2022 |
@
Mount Vernon #19
|
L 0-47 | Mount Vernon 1st Street Field | |
| 10/21/2022 |
vs
Benton #136
|
W 21-14 | Central DeWitt High School | Senior Night |
| 10/28/2022 |
vs
Mount Vernon #19
|
L 9-23 | Van Metre Field-Ash Park (Cornell College) | 3A - First Round |
