| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 8/19/2022 |
@
North Mahaska #272
|
7:00 PM CT | Cardinal High School | Scrimmage |
| 8/26/2022 |
vs
Pekin #275
|
L 0-20 | Pekin Community High School | |
| 9/2/2022 |
vs
Central Lee #281
|
L 14-34 | Cardinal High School | |
| 9/9/2022 |
@
Davis County #280
|
L 6-16 | Davis County High School Mustang Stadium - Davis County High School | |
| 9/16/2022 |
vs
Central Decatur #152
|
L 20-56 | Cardinal High School | Homecoming |
| 9/23/2022 |
@
Van Buren County #267
|
L 16-22 | Van Buren County High School Van Buren County High School | Homecoming |
| 9/30/2022 |
vs
Sigourney Keota #63
|
L 3-56 | Cardinal High School | Tackle Cancer Night |
| 10/7/2022 |
@
Pella Christian #65
|
L 0-63 | Pella Christian High School | |
| 10/14/2022 |
vs
Pleasantville #186
|
L 17-50 | Cardinal High School | Senior Night |
| 10/21/2022 |
vs
Colfax-Mingo #297
|
L 7-41 | Cardinal High School | Teacher Appreciation/Youth Football Night |
