| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 3/31/2022 |
@
Solon #53
|
L 0-4 | Solon CSD Spartan Stadium | Varsity only |
| 4/2/2022 |
vs
North Scott #24
|
L 0-5 | The Pitch @ North Scott | |
| 4/7/2022 |
@
Prairie #5
|
L 0-6 | Cedar Rapids Prairie High School | Varsity Only |
| 4/8/2022 |
@
Hillcrest Academy #145
|
W 1-0 | Hillcrest Academy | OT Pks |
| 4/11/2022 |
vs
Monticello #172
|
W 9-0 | Iowa City Regina High School | |
| 4/19/2022 |
vs
Columbus Catholic #67
|
W 2-1 | Iowa City Regina High School | OT, PKs |
| 4/22/2022 |
@
Mount Pleasant #165
|
W 10-0 | Mt. Pleasant - East Lake Park | |
| 4/26/2022 |
vs
Bettendorf #14
|
L 0-3 | Iowa City Regina High School | |
| 4/28/2022 |
@
West Liberty #46
|
W 2-1 | West Liberty High School | |
| 4/30/2022 |
vs
Assumption #22
|
8:00 AM CT | Assumption High School | Catholic Schools Tournament |
| 4/30/2022 |
vs
Beckman Catholic #47
|
L 1-2 | Assumption High School | |
| 4/30/2022 |
vs
Burlington Notre Dame #40
|
L 0-1 | St. Vincent Athletic Complex | Catholic Invitational |
| 4/30/2022 |
vs
St. Albert #118
|
W 4-0 | St. Vincent Athletic Complex | Catholic School Invitational Tournament |
| 5/3/2022 |
vs
Mid-Prairie #82
|
W 4-1 | Iowa City Regina High School | |
| 5/4/2022 |
vs
Davenport Central #37
|
L 0-3 | Iowa City Regina High School | Rescheduled. |
| 5/7/2022 |
vs
Gilbert #31
|
L 1-2 | Nevada High School | Nevada Tournament |
| 5/7/2022 |
vs
Perry #49
|
L 1-4 | Nevada SCORE Recreation Complex | |
| 5/7/2022 |
vs
Collins-Maxwell #135
|
W 5-1 | Nevada SCORE Recreation Complex | |
| 5/10/2022 |
vs
Pleasant Valley #1
|
L 0-5 | Iowa City Regina High School | |
| 5/13/2022 |
@
Muscatine #12
|
L 0-2 | Muscatine Soccer Complex | MHS Senior Night |
| 5/19/2022 |
vs
Anamosa #160
|
W 10-0 | Iowa City Regina High School | 1A-3 First Round |
| 5/23/2022 |
vs
Columbus Catholic #67
|
W 1-0 | Iowa City Regina High School | 1A-3 Second Round |
| 5/25/2022 |
vs
Beckman Catholic #47
|
L 0-1 | Beckman Catholic High School | 1A-3 Championship |
